Isovaleryl chloride → N-(4-(5-Cyano-1-methyl-1H-pyrrol-2-yl)phenyl)-3-methylbutanamide
反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([CH3:13])[C:11]([C:14]#[N:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[CH3:16][CH:17]([CH3:22])[CH2:18][C:19](Cl)=[O:20]>>[C:14]([C:11]1[N:12]([CH3:13])[C:8]([C:5]2[CH:6]=[CH:7][C:2]([NH:1][C:19](=[O:20])[CH2:18][CH:17]([CH3:22])[CH3:16])=[CH:3][CH:4]=2)=[CH:9][CH:10]=1)#[N:15]参加物
3
実験手順
The title compound was prepared according to the general procedure for acylation of 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile using 3-methyl-butyryl chloride (67 μL, 0.55 mmol) to provide N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]-3-methyl butanamide (0.042 g).
後処理
- customThe title compound was prepared
出典と根拠
- ORDレコード
- ord-85b5854606e649e48862b133ed7e8a84
- 出典データセット
- uspto-grants-2007_11
- 特許番号
- US07297713B2
反応ノート
読み込み中…