4-Pyridinemethanamine → HCID 178470220、化合物

HRID 1595330

反応式

HRID 1595330 の反応式
O[N:2]=[C:3]([C:9]([C:11]1[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=1)=O)[C:4]([O:6][CH2:7][CH3:8])=[O:5].[NH2:18][CH2:19][C:20]1[CH:25]=[CH:24][N:23]=[CH:22][CH:21]=1>C1(C)C(C)=CC=CC=1>[CH3:17][C:14]1[CH:15]=[CH:16][C:11]([C:9]2[NH:18][C:19]([C:20]3[CH:25]=[CH:24][N:23]=[CH:22][CH:21]=3)=[N:2][C:3]=2[C:4]([O:6][CH2:7][CH3:8])=[O:5])=[CH:12][CH:13]=1

参加物

4

反応物 2

HCID 773174-PyridinemethanamineHCID 178472891HCID 178472891、化合物

生成物 1

HCID 178470220HCID 178470220、化合物収率 395.1%

試薬・触媒・溶媒 1

HCID 7237O-Xylene溶媒

実験手順

Ethyl 2-hydroxyimino-3-(4-methylphenyl)-3-oxopropionate (10.5 g) and 4-aminomethylpyridine (5.8 g) were dissolved in xylene (100 ml), and the mixture was reacted and treated in the same manner as in Starting Material Synthetic Example 1 to give ethyl 5-(4-methylphenyl)-2-(4-pyridyl)imidazole-4-carboxylate (54.2 g), melting point 182-185° C.

後処理

  1. customthe mixture was reacted
  2. additiontreated in the same manner as

出典と根拠

ORDレコード
ord-0edcf67e3f364e86ac4595f59cc055d0
出典データセット
uspto-grants-2001_09
特許番号
US06288061B1

関連ノート

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