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HRID 1595656作成日：2026年10月27日

Bis(2-chloroethyl)ethylamine → 4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-piperidine-4-carboxylic acid ethyl ester

https://huagongshe.com/reaction/1595656

反応式

関与物質

役割名称HCID仕込み量
反応物Bis(2-chloroethyl)ethylamineHCID 10848—
反応物[4-(4-Chloro-phenoxy)-benzenesulfonyl]-acetic acid ethyl esterHCID 11121795—
生成物4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-piperidine-4-carboxylic acid ethyl esterHCID 11762171—

反応手順

4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-piperidine-4-carboxylic acid ethyl ester was prepared according to the general method outlined in example 83 starting from [4-(4-chloro-phenoxy)-benzenesulfonyl]-acetic acid ethyl ester (4 g, 11.3 mmol) and ethyl-bis-(2-chloro-ethyl)-amine (2.32 g, 16.9 mmol). Yield 3.36 g (66%); brown oil; MS: 452.0 (M+H)+

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06288086B1
出典データセットuspto-grants-2001_09
ORD IDord-38e57f5b266a4937b34145bdea9c680f
出典メモuspto-grants-2001_09