化工社化工社 化学情報印刷レポート · 研究参考用
Phenylpropanolamine → (1S,2R)-2-amino-1-phenylpropan-1-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phenylpropanolamine | HCID 10297 | — |
| 反応物 | Sodium borohydride | HCID 4311764 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | (1S,2R)-2-amino-1-phenylpropan-1-ol | HCID 26934 | — |
反応手順
As shown in the scheme above, (1R, 2S)-(−)- norephedrine is reacted with an optionally substituted benzaldehyde by refluxing in ethanol, and reducing the product of that reaction with sodium borohydride at ambient temperature to produce the desired norephedrine derivative compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06288233B1 |
| 出典データセット | uspto-grants-2001_09 |
| ORD ID | ord-b28c151d057f4f0bbcfc10c69ab8201e |
| 出典メモ | uspto-grants-2001_09 |