化工社化工社 化学情報印刷レポート · 研究参考用
3,7-Dibenzyl-3,7-diazabicyclo[3.3.1]nonane → 3-Benzyl-3,7-diazabicyclo[3.3.1]nonane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3,7-Dibenzyl-3,7-diazabicyclo[3.3.1]nonane | HCID 47341 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Palladium | HCID 23938 | — |
| 生成物 | 3-Benzyl-3,7-diazabicyclo[3.3.1]nonane | HCID 13059482 | — |
反応手順
3,7-Dibenzyl-3,7-diazabicyclo[3.3.1]nonane (1.97 g; 6.4 mmol; from step (a) above) was dissolved in EtOH (95%) and hydrogenated over 5% Pd/C at 1 atm. until tlc indicated that the reaction was complete. The catalyst was removed by filtration through a pad of celite and the residue was concentrated under reduced pressure to give the title compound in a quantitative yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06291475B1 |
| 出典データセット | uspto-grants-2001_09 |
| ORD ID | ord-8850405cfb6b47c9aa35a303e49512b9 |
| 出典メモ | uspto-grants-2001_09 |