反応式
[CH3:1][O:2][C:3]1[C:4]([C:10]([O:12]C)=O)=[N:5][CH:6]=[C:7]([CH3:9])[N:8]=1.[NH3:14]>>[CH3:1][O:2][C:3]1[C:4]([C:10]([NH2:14])=[O:12])=[N:5][CH:6]=[C:7]([CH3:9])[N:8]=1参加物
3
反応条件
- 温度
- 50 °C
実験手順
1 g (5.5 mmol) of methyl 3-methoxy-5-methylpyrazine-carboxylate was initially charged in 15 ml (198 mmol) of NH3 (25%) and the mixture was stirred at 50° C. After concentration, 0.8 g of 3-methoxy-5-methylpyrazine-2-carboxamide was obtained. The yield was 86 percent. Other data concerning the title product was:
後処理
- concentrationAfter concentration
出典と根拠
- ORDレコード
- ord-3fd488a37a2049d980cdd56963b94027
- 出典データセット
- uspto-grants-2001_09
- 特許番号
- US06291674B1
関連ノート
読み込み中…