Aluminium lithium hydride → 3-(1H-indol-2-yl)butan-1-amine

HRID 1596775ノート

反応式

HRID 1596775 の反応式
N1C2C(=CC=CC=2)C=C1CCCN.[NH:14]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:16]=[C:15]1[CH:23]([CH3:28])[CH2:24][C:25]([NH2:27])=O.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[NH:14]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:16]=[C:15]1[CH:23]([CH3:28])[CH2:24][CH2:25][NH2:27]

参加物

4

反応物 3

HCID 21226445Aluminium lithium hydrideHCID 217030923-Indolyl-butyramideHCID 223118203-(1H-indol-2-yl)propan-1-amine

生成物 1

HCID 702033103-(1H-indol-2-yl)butan-1-amine収率 75%

実験手順

This compound was prepared in in the manner described above for (19a) using 3-indolyl-butyramide and lithium aluminum hydride. A 75% yield was obtained as a yellow solid: mp 51-53° C.

後処理

  1. customThis compound was prepared in in the manner
  2. customA 75% yield was obtained as a yellow solid

出典と根拠

ORDレコード
ord-9123a109bc13406885275f53e8b6b615
出典データセット
uspto-grants-2001_09
特許番号
US06291683B1

反応ノート

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