4-Benzyl-3,5-dichloronitrobenzene → 2-Methyl-5-[4-(2,6-dichloro-4-nitrobenzyl)benzoyl]pyridine

反応式

[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][N:3]=1.[CH2:11]([C:18]1[C:23]([Cl:24])=[CH:22][C:21]([N+:25]([O-:27])=[O:26])=[CH:20][C:19]=1[Cl:28])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](=[O:7])[C:15]2[CH:16]=[CH:17][C:12]([CH2:11][C:18]3[C:19]([Cl:28])=[CH:20][C:21]([N+:25]([O-:27])=[O:26])=[CH:22][C:23]=3[Cl:24])=[CH:13][CH:14]=2)=[CH:4][N:3]=1

参加物

反応物 2

HCID 216993324-Benzyl-3,5-dichloronitrobenzene

HCID 218904586-Methylnicotinoyl chloride

生成物 1

HCID 216994232-Methyl-5-[4-(2,6-dichloro-4-nitrobenzyl)benzoyl]pyridine収率 14.8%

実験手順

The title compound was prepared as pale yellow crystals at yield of 14.8%, in a similar manner as in Reference Eample 1, by the reaction of 6-methylnicotinoylchloride and 4-benzyl-3,5-dichloronitrobenzene.

出典と根拠

ORDレコード: ord-78a5533e351240538036c13915c2794f
出典データセット: uspto-grants-2001_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06294536B1

反応ノート

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