Sulfanilamide → 4-sulfamoyl-N-[4-(2-furyl)benzylidene]aniline

HRID 1597509ノート

反応式

HRID 1597509 の反応式
[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[O:10][CH:11]=[CH:12][CH:13]=2)=[CH:5][CH:4]=1)=O.[S:14]([NH2:24])(=[O:23])([C:16]1[CH:21]=[CH:20][C:19]([NH2:22])=[CH:18][CH:17]=1)=[O:15]>C(O)C>[S:14]([C:16]1[CH:21]=[CH:20][C:19]([N:22]=[CH:1][C:3]2[CH:8]=[CH:7][C:6]([C:9]3[O:10][CH:11]=[CH:12][CH:13]=3)=[CH:5][CH:4]=2)=[CH:18][CH:17]=1)(=[O:15])(=[O:23])[NH2:24]

参加物

4

反応物 2

HCID 5333SulfanilamideHCID 27722954-(Furan-2-yl)benzaldehyde

生成物 1

HCID 223167314-sulfamoyl-N-[4-(2-furyl)benzylidene]aniline

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of 2-(4-formylphenyl)furan (0.335 g, 1.95 mmol, prepared according to the method of Heterocycles, 1990, 31, 1951), sulfanilamide (0.336 g, 1.95 mmol) in ethanol (8 mL) was heated at reflux temperature for 2.5 hour. After cooling to room temperature, the crystals which collected by filtration and washed with ethanol to give the subtitle compound (0.378 g).

後処理

  1. customprepared
  2. temperaturewas heated
  3. temperatureat reflux temperature for 2.5 hour
  4. filtrationthe crystals which collected by filtration
  5. washwashed with ethanol

出典と根拠

ORDレコード
ord-4b2146605c0d4fc382fab3c6ca03b6b5
出典データセット
uspto-grants-2001_09
特許番号
US06294558B1

反応ノート

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