Bromine → 2-Bromo-1-(4-bromo-2-methoxyphenyl)ethanone
反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:10])[CH3:9])=[C:4]([O:11][CH3:12])[CH:3]=1.[Br:13]Br>O1CCOCC1>[Br:13][CH2:9][C:8]([C:5]1[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][C:4]=1[O:11][CH3:12])=[O:10]参加物
4
実験手順
To a stirred solution of 1-(4-bromo-2-methoxyphenyl)-1-ethanone (31.5 g, 138 mmol) in dioxane (32 ml) was added a solution of bromine (21.8 g, 136 mmol) in dioxane (123 ml), and the mixture was stirred for 3 hours. Then the volatile was evaporated in vacuo. The residue was recystallized with hexane-dichloromethane to give title compound (32.1 g, 76% yield).
後処理
- customThen the volatile was evaporated in vacuo
出典と根拠
- ORDレコード
- ord-21eb4ba799954e0da3d856214a5d89e0
- 出典データセット
- uspto-grants-2001_09
- 特許番号
- US06294558B1
反応ノート
読み込み中…