Hydrochloric Acid → 4-(2-Aminothiazol-4-yl)butanoic acid hydrochloride

反応式

[NH2:1][C:2]1[S:3][CH:4]=[C:5]([CH2:7][CH2:8][CH2:9][C:10]([O:12]C)=[O:11])[N:6]=1.[ClH:14]>>[ClH:14].[NH2:1][C:2]1[S:3][CH:4]=[C:5]([CH2:7][CH2:8][CH2:9][C:10]([OH:12])=[O:11])[N:6]=1

参加物

反応物 2

HCID 313Hydrochloric Acid

HCID 21699734Methyl 4-(2-amino-1,3-thiazol-4-yl)butanoate

生成物 1

HCID 867544654-(2-Aminothiazol-4-yl)butanoic acid hydrochloride

実験手順

Ester 1-3 (1.3 g, 6.5 mmol) was dissolved in 32 mL 6 N HCl. After stirring overnight, the resulting suspension was concentrated, providing acid 1-4 as a white solid.

後処理

concentrationthe resulting suspension was concentrated

出典と根拠

ORDレコード: ord-26fe444ea8c84e3c97b508ce0cb6f602
出典データセット: uspto-grants-2001_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06294549B1

反応ノート

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