Ethanol → 2-(6-Methyl-1H-indol-3-yl)ethan-1-amine

HRID 1597915ノート

反応式

HRID 1597915 の反応式
[CH3:1][C:2]1[C:10](Br)=[C:9]2[C:5]([C:6]([CH2:12][CH2:13][NH2:14])=[CH:7][NH:8]2)=[CH:4][CH:3]=1.C(O)C>C(N(CC)CC)C>[CH3:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH2:12][CH2:13][NH2:14])=[CH:7][NH:8]2)=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 702EthanolHCID 15274383HCID 15274383、化合物

生成物 1

HCID 1900062-(6-Methyl-1H-indol-3-yl)ethan-1-amine

試薬・触媒・溶媒 1

HCID 8471Triethylamine溶媒

実験手順

A sample of 6-methyl-7-bromo-1H-indole-3-ethanamine was contacted with Pd/C H2 in the presence of ethanol and triethylamine. The resulting material was evaporated and partitioned between base/CHCl3. The organic phase was dried, concentrated, and dried. The resulting material was taken up into methanol and added to ethereal HCl. The resulting material was washed and vacuum dried.

後処理

  1. customThe resulting material was evaporated
  2. custompartitioned between base/CHCl3
  3. customThe organic phase was dried
  4. concentrationconcentrated
  5. customdried
  6. additionadded to ethereal HCl
  7. washThe resulting material was washed
  8. customvacuum dried

出典と根拠

ORDレコード
ord-cf5ab7a645444cfd928f3ee88ae6d89c
出典データセット
uspto-grants-1998_04
特許番号
US05736544

反応ノート

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