Sulfuric Acid → 2-Amino-5-bromobenzenesulphonic acid

HRID 1599168ノート

反応式

HRID 1599168 の反応式
[Br:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.[S:9](=O)(=[O:12])([OH:11])[OH:10]>ClC1C=CC=CC=1Cl>[NH2:6][C:5]1[CH:7]=[CH:8][C:2]([Br:1])=[CH:3][C:4]=1[S:9]([OH:12])(=[O:11])=[O:10]

参加物

4

反応物 2

HCID 1118Sulfuric AcidHCID 78074-Bromoaniline

生成物 1

HCID 150236152-Amino-5-bromobenzenesulphonic acid

試薬・触媒・溶媒 1

HCID 72391,2-Dichlorobenzene溶媒

反応条件

温度
180 °C

実験手順

A mixture containing 31 g (180 mmol) of 4-bromoaniline and 9.7 ml (220 mmol) of sulphuric acid in 200 ml of 1,2-dichlorobenzene is heated at 180° C. for 6 hours. The reaction medium is allowed to cool to room temperature and is then filtered. The residue is washed with dichloromethane.

後処理

  1. temperatureto cool to room temperature
  2. filtrationis then filtered
  3. washThe residue is washed with dichloromethane

出典と根拠

ORDレコード
ord-38ec545041f24c8ebae64595f1b31983
出典データセット
uspto-grants-1998_04
特許番号
US05739382

反応ノート

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