Prenderol → 5,5-Diethyl-2-(4-nitrobenzyl)-1,3,2-dioxaphosphorinan-2-oxide

反応式

[N+:1]([C:4]1[CH:14]=[CH:13][C:7]([CH2:8][P:9](=[O:12])([OH:11])[OH:10])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH2:15]([C:17]([CH2:22][CH3:23])([CH2:20]O)[CH2:18]O)[CH3:16]>>[CH2:15]([C:17]1([CH2:22][CH3:23])[CH2:20][O:11][P:9](=[O:10])([CH2:8][C:7]2[CH:13]=[CH:14][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=2)[O:12][CH2:18]1)[CH3:16]

参加物

反応物 2

HCID 8284Prenderol

HCID 5180708(4-Nitro-benzyl)-phosphonic acid

生成物 1

HCID 189281005,5-Diethyl-2-(4-nitrobenzyl)-1,3,2-dioxaphosphorinan-2-oxide

実験手順

With 4-nitrobenzylphosphonic acid and 2,2-diethyl-1,3-propanediol, the same procedure as in Reference Example 11 was followed, to yield diethyl-2-(4-nitrobenzyl)-1,3,2-dioxaphosphorinane-2-oxide, which was then recrystallized from ethanol-hexane to yield colorless prisms having a melting point of 159° to 160° C.

出典と根拠

ORDレコード: ord-8308a6decc3f48919a8e96a999fc49e2
出典データセット: uspto-grants-1998_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05741784

反応ノート

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