Thiourea → HCID 21699321、化合物
反応式
[NH2:1][C:2]([NH2:4])=[S:3].[Cl:5][C:6]1[C:7](=[O:15])[NH:8][C:9](=[O:14])[NH:10][C:11]=1[CH2:12]Cl>C(O)C>[ClH:5].[Cl:5][C:6]1[C:7](=[O:15])[NH:8][C:9](=[O:14])[NH:10][C:11]=1[CH2:12][S:3][C:2](=[NH:4])[NH2:1]参加物
4
実験手順
To a solution of 140 mg of thiourea in ethanol (3 ml), 300 mg of 5-chloro-6-chloromethyluracil were added, followed by heating for 6 hours under reflux. After the reaction mixture was allowed to cool down, a crystallized matter was collected by filtration, whereby 337 mg of the title compound were obtained (yield: 81%).
後処理
- temperatureby heating for 6 hours
- temperatureunder reflux
- temperatureto cool down
- filtrationa crystallized matter was collected by filtration
出典と根拠
- ORDレコード
- ord-ad7ed1497fbb4fcc95f6bca901ab5dbe
- 出典データセット
- uspto-grants-1998_04
- 特許番号
- US05744475
反応ノート
読み込み中…