Imidazole → Diethyl 3-(tert-Butyldimethylsilyloxy)glutarate

HRID 1600351

反応式

HRID 1600351 の反応式
N1C=CN=C1.[C:6]([Si:10](Cl)([CH3:12])[CH3:11])([CH3:9])([CH3:8])[CH3:7].[OH:14][CH:15]([CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])[CH2:16][C:17]([O:19][CH2:20][CH3:21])=[O:18]>C(Cl)Cl>[Si:10]([O:14][CH:15]([CH2:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])([C:6]([CH3:9])([CH3:8])[CH3:7])([CH3:12])[CH3:11]

参加物

5

反応物 3

HCID 795ImidazoleHCID 28928tert-Butyldimethylsilyl chlorideHCID 96259Diethyl 3-hydroxyglutarate

生成物 1

HCID 13327289Diethyl 3-(tert-Butyldimethylsilyloxy)glutarate

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

Imidazole and tert-butylchlorodimethylsilane are added to a solution of diethyl 3-hydroxyglutarate in methylene chloride, and the reaction is performed to give diethyl 3-[(tert-butydimethylsilyl)-oxy]pentanedioate.

出典と根拠

ORDレコード
ord-74225625011f4fc3918d63a785f63c5e
出典データセット
uspto-grants-1998_04
特許番号
US05744604

関連ノート

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