2-Naphthalenethiol → HCID 21830630、化合物

HRID 1600893ノート

反応式

HRID 1600893 の反応式
[CH:1]1[CH:10]=[C:9]2[C:4]([CH:5]=[C:6]([SH:11])[CH:7]=[CH:8]2)=[CH:3][CH:2]=1.[N:12]1[CH:17]=[CH:16][CH:15]=[C:14]([CH2:18][CH2:19][C:20](=[O:23])[CH:21]=[CH2:22])[CH:13]=1>C(O)C>[N:12]1[CH:17]=[CH:16][CH:15]=[C:14]([CH2:18][CH2:19][C:20](=[O:23])[CH2:21][CH2:22][S:11][C:6]2[CH:7]=[CH:8][C:9]3[C:4](=[CH:3][CH:2]=[CH:1][CH:10]=3)[CH:5]=2)[CH:13]=1

参加物

4

反応物 2

HCID 70582-NaphthalenethiolHCID 218306261-(3-Pyridyl)-4-penten-3-one

生成物 1

HCID 21830630HCID 21830630、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

2-Thionaphthol was added to a solution of 1-(3-pyridyl)-4-penten-3-one (0.200 g) in ethanol (30 ml) followed by stirring overnight at room temperature. The ethanol was removed under reduced pressure and the residue purified by column chromatography over silica eluting with dichloromethane:ethyl acetate (2:1) to give the sub-title compound as a white solid (0.142 g).

後処理

  1. customThe ethanol was removed under reduced pressure
  2. customthe residue purified by column chromatography over silica eluting with dichloromethane:ethyl acetate (2:1)

出典と根拠

ORDレコード
ord-59a8a781c3df46478763d2b69215da3e
出典データセット
uspto-grants-1999_11
特許番号
US05977105

反応ノート

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