関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Benzaldehyde | HCID 240 | — |
| 反応物 | Ethyl cyanoacetate | HCID 7764 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Sodium aluminosilicate | HCID 72941443 | — |
| 生成物 | Ethyl benzylidenecyanoacetate | HCID 74845 | 98% |
反応手順
10.61 g of benzaldehyde (0.1 mol) and 11.31 g of ethyl cyanoacetate (0.1 mol) are placed in a flask equipped with a reflux condenser and heated to 90° C. 1.0 g of zeolite A (supplied by Merck: MS 3 Å) and 0.5 g of K2CO3 are then added in succession. The reaction starts immediately and is complete after about 4 minutes. The reaction mixture is filtered while still hot, giving ethyl cyanocinnamate in a purity of >96%. The yield is 98%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05977290 |
|---|
| 出典データセット | uspto-grants-1999_11 |
|---|
| ORD ID | ord-48599a4b195b4f949db63b55e7d7669b |
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| 出典メモ | uspto-grants-1999_11 |
|---|
