関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Formic Acid | HCID 284 | — |
| 反応物 | Formamide | HCID 713 | — |
| 反応物 | Sodium Dithionite | HCID 24489 | — |
| 反応物 | 6-Amino-1,3-bis(cyclopropylmethyl)uracil | HCID 18624515 | — |
| 反応物 | Sodium Nitrite | HCID 23668193 | — |
| 生成物 | 1,3-Dicyclopropylmethyl xanthine | HCID 15291303 | — |
反応手順
1,3-Di-cyclopropylmethyl xanthine was prepared using an analogous procedure to that described in Chem. Berichte 88, 1306-1312, 1955: 20.2 g (0.0855 mol) of 1,3-di-cyclopropylmethyl-6-amino-uracil was dissolved in 100 ml of formamide, then 5.9 g sodium nitrite was added and at 60° C. 13.4 ml formic acid was added slowly with stirring. After the colour had changed from yellow to violet, the mixture was heated up to 100° C. and 3.1 g of sodium dithionite (Na2S2O4) was added in small portions.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05981535 |
|---|
| 出典データセット | uspto-grants-1999_11 |
|---|
| ORD ID | ord-40bb0d42285548b88b7e404452799203 |
|---|
| 出典メモ | uspto-grants-1999_11 |
|---|
