Cyclopropanecarbonyl chloride → 1,2,3,4-Tetrahydro-1-methoxymethyl-6,7-dimethoxyisoquinoline
反応式
[CH:1]1([CH:4]2[C:13]3[C:8](=[CH:9][C:10]([O:16][CH3:17])=[C:11]([O:14][CH3:15])[CH:12]=3)[CH2:7][CH2:6][NH:5]2)CC1.[CH3:18][O:19]CC(Cl)=O.C1(C(Cl)=O)CC1>>[CH3:18][O:19][CH2:1][CH:4]1[C:13]2[C:8](=[CH:9][C:10]([O:16][CH3:17])=[C:11]([O:14][CH3:15])[CH:12]=2)[CH2:7][CH2:6][NH:5]1参加物
4
実験手順
1,2,3,4-Tetrahydro-1-methoxymethyl-6,7-dimethoxyisoquinoline was prepared by a procedure analogous to that described in example 4 for 1,2,3,4-tetrahydro-1-cyclopropyl- 6,7-dimethoxy-isoquinoline but substituting in the first step 2-methoxyacetyl chloride for cyclopropylcarbonyl chloride.
出典と根拠
- ORDレコード
- ord-f1beabbdaf5c48ab86a7f27c06a1b0fd
- 出典データセット
- uspto-grants-1999_11
- 特許番号
- US05981521
反応ノート
読み込み中…