Hydrogen iodide → HCID 19610257、化合物
反応式
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH:8]([C:14]([O:16][CH3:17])=[O:15])[NH:9][CH:10]2[CH3:13])=[CH:5][CH:4]=1.[IH:18]>CO>[IH:18].[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH:8]([C:14]([O:16][CH3:17])=[O:15])[NH:9][CH:10]2[CH3:13])=[CH:5][CH:4]=1参加物
4
実験手順
To a solution of 1,2,3,4-tetrahydro-7-methoxy-3-methoxycarbonyl-1-methyl-isoquinoline (0.526 g, 2.24 mmol) in methanol (10 mL) cooled to 0° C. was added dropwise a solution of 57% HI solution (0.33 mL). The ice bath was removed and the solution was stirred at rt for 20 min. To the bright orange solution was added ether (100 mL) and the mixture was stirred for 10 min. The light yellow precipitate was filtered and dried in vacuo (P2O5) to give the desired salt (0.736 g).
後処理
- customThe ice bath was removed
- additionTo the bright orange solution was added ether (100 mL)
- stirringthe mixture was stirred for 10 min
- filtrationThe light yellow precipitate was filtered
- dry with materialdried in vacuo (P2O5)
出典と根拠
- ORDレコード
- ord-1cd2963fbf374d3ea3ee276fbd69043d
- 出典データセット
- uspto-grants-1999_11
- 特許番号
- US05981521
反応ノート
読み込み中…