1,1-Bis(benzyloxy)trimethylamine → HCID 178484264、化合物

HRID 1602249

反応式

HRID 1602249 の反応式
[NH2:1][C:2]1[NH:6][N:5]=[C:4]([C:7]2[CH:12]=[CH:11][C:10]([N+:13]([O-:15])=[O:14])=[CH:9][CH:8]=2)[C:3]=1[C:16]#[N:17].C(O[CH:26](OCC1C=CC=CC=1)[N:27]([CH3:29])[CH3:28])C1C=CC=CC=1>C1(C)C=CC=CC=1>[N+:13]([C:10]1[CH:9]=[CH:8][C:7]([C:4]2[C:3]([C:16]#[N:17])=[C:2]([N:1]=[CH:26][N:27]([CH3:29])[CH3:28])[NH:6][N:5]=2)=[CH:12][CH:11]=1)([O-:15])=[O:14]

参加物

4

反応物 2

HCID 748371,1-Bis(benzyloxy)trimethylamineHCID 178509386HCID 178509386、化合物

生成物 1

HCID 178484264HCID 178484264、化合物

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

In 1 ml of toluene, 57.3 mg (0.25 mmol) of 5-amino-3-(4-nitro-phenyl)-1H-pyrazole-4-carbonitrile and 79.3 μl of N,N-dimethylformamide dibenzylacetal are boiled overnight. Filtering of the suspension and washing with hexane yield N'-[3-(4-nitro-phenyl)-4-cyano-1H-pyrazol-5-yl]-N,N-dimethylformamidine; TLC: Rf =0.15 (ethyl acetate:hexane=2:1); TRet (Grad20-100)=8.8.

後処理

  1. filtrationFiltering of the suspension
  2. washwashing with hexane

出典と根拠

ORDレコード
ord-d4a79f1b57114cb8b3706a09b566e770
出典データセット
uspto-grants-1999_11
特許番号
US05981533

関連ノート

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