Hydrochloric Acid → 2-(2,3-Dihydro-1-benzofuran-4-yl)ethan-1-ol
反応式
O[CH2:2][CH2:3][C:4]1[C:9]([CH2:10][CH2:11][OH:12])=[CH:8][CH:7]=[CH:6][C:5]=1[OH:13].Cl>O>[O:13]1[C:5]2[CH:6]=[CH:7][CH:8]=[C:9]([CH2:10][CH2:11][OH:12])[C:4]=2[CH2:3][CH2:2]1参加物
4
実験手順
A mixture of 2,3-bis(2-hydroxyethyl)-phenol (1.2 g) and 36% aqueous hydrochloric acid (24 ml) was heated at reflux for 2 h. The mixture was cooled, diluted with water (24 ml) and extracted with ethyl acetate (2×24 ml). The combined extracts were dried (Na2SO4) and the solvent evaporated to give the title compound (1.2 g) as a brown oil.
後処理
- temperaturewas heated
- temperatureat reflux for 2 h
- temperatureThe mixture was cooled
- extractionextracted with ethyl acetate (2×24 ml)
- dry with materialThe combined extracts were dried (Na2SO4)
- customthe solvent evaporated
出典と根拠
- ORDレコード
- ord-63735aa97acc44b78ed54b56931a4332
- 出典データセット
- uspto-grants-1999_11
- 特許番号
- US05981572
反応ノート
読み込み中…