関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | Biphenyl | HCID 7095 | — |
| 反応物 | 4-Chlorobenzenesulfonyl chloride | HCID 7398 | — |
| 溶媒 | 1,2,3-Trichlorobenzene | HCID 6895 | — |
| 生成物 | 4-(4'-Chlorobenzenesulphonyl)biphenyl | HCID 630022 | 65% |
反応手順
A mixture of biphenyl (10 g, 0.065 mol) and 4-chlorobenzenesulphonyl chloride (13.69 g, 0.065 mol) in trichlorobenzene (3 mL) was heated with stirring to 110° C. Anhydrous ferric chloride (0.05 g, 0.0003 mmol) was added and stirring was continued at 150° C. for 16 h. The cooled solid was stirred with methanol (200 mL). The product was filtered, washed with methanol, dried, and recrystallised from acetic acid to give 4-(4′-chlorobenzenesulphonyl)biphenyl (13.9 g, 65%); m.p. 169° C. (lit. 171-173° C.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07736539B2 |
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| 出典データセット | uspto-grants-2010_06 |
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| ORD ID | ord-75e276f8a4ae412098a9bb92b19f2df9 |
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| 出典メモ | uspto-grants-2010_06 |
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