7-Methylimidazo[5,1-b]thiazole → HCID 18395215、化合物
反応式
C(OC([O:7][C@@H:8]([C@H:10]1[C:25](=[O:26])[N:12]2[C:13]([C:19]([O:21]CC=C)=[O:20])=[C:14]([CH2:17]O)[C@H:15]([CH3:16])[C@H:11]12)[CH3:9])=O)C=C.[CH3:27][C:28]1[N:29]=[CH:30][N:31]2[CH:35]=[CH:34][S:33][C:32]=12>>[OH:7][C@@H:8]([C@H:10]1[C:25](=[O:26])[N:12]2[C:13]([C:19]([O-:21])=[O:20])=[C:14]([CH2:17][N:29]3[C:28]([CH3:27])=[C:32]4[S:33][CH:34]=[CH:35][N+:31]4=[CH:30]3)[C@H:15]([CH3:16])[C@H:11]12)[CH3:9]参加物
3
実験手順
The same procedure as in Example 1 was repeated except that 103 mg of allyl (1S,5R,6S)-6-[(1R)-1-allyloxycarbonyloxyethyl]-2-hydroxymethyl-1-methyl-1-carbapen-2-em-3-carboxylate and 117 mg of 7-methylimidazo[5,1-b]thiazole were used, thereby obtaining 7.8 mg of the title compound.
出典と根拠
- ORDレコード
- ord-3ee2f30863f34bbc8a22794789504104
- 出典データセット
- uspto-grants-1999_11
- DOI