化工社化工社 化学情報印刷レポート · 研究参考用
Chlorotrimethylsilane → N,N-Diethyl-2-(trimethylsilyl)-1-naphthalenecarboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Chlorotrimethylsilane | HCID 6397 | — |
| 反応物 | N,N-Diethyl-1-naphthamide | HCID 229388 | — |
| 生成物 | N,N-Diethyl-2-(trimethylsilyl)-1-naphthalenecarboxamide | HCID 15828028 | 71% |
反応手順
N,N-Diethyl-1-naphthalenecarboxamide was reacted with 2 eq TMSCl according to General Method A. The resulting reaction mixture was worked up in the usual manner, then purified by chromatography with 20% ethyl acetate/80% hexanes to afford 2.1 g of the desired compound as a clear oil, a 71% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05994270 |
| 出典データセット | uspto-grants-1999_11 |
| ORD ID | ord-3e590ffdfe7c427881eabbc3eee42cca |
| 出典メモ | uspto-grants-1999_11 |