化工社化工社 化学情報印刷レポート · 研究参考用
Chlorotrimethylsilane → N-Ethyl-2-(trimethylsilyl)-1-naphthalenecarboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Chlorotrimethylsilane | HCID 6397 | — |
| 反応物 | N-ethyl-1-naphthalenecarboxamide | HCID 4088726 | — |
| 生成物 | N-Ethyl-2-(trimethylsilyl)-1-naphthalenecarboxamide | HCID 19602329 | 58% |
反応手順
N-Ethyl-1-naphthalenecarboxamide was reacted with 2 eq TMSCl according to General Method C. The resulting reaction mixture was worked up in the usual manner, then purified by recrystallization from cold ethyl acetate/hexanes to afford 1.6 g of desired compound as a white solid, a 58% yield. m.p. 141-143° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05994270 |
| 出典データセット | uspto-grants-1999_11 |
| ORD ID | ord-632443465f9a46ed8b8d291916272c7f |
| 出典メモ | uspto-grants-1999_11 |