Water → HCID 15581960、化合物
反応式
[CH2:1]([NH2:4])[CH:2]=[CH2:3].[N:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[CH2:11][C:12](N)=[S:13].O>C(O)C>[CH2:1]([NH:4][C:12](=[S:13])[CH2:11][C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][N:5]=1)[CH:2]=[CH2:3]参加物
5
実験手順
Allylamine (3.1 g.) is added with stirring to 4.0 g. of 2-(2-pyridyl)thioacetamide in 20 ml. of water at 0°C. The resulting mixture is allowed to stand overnight at 5°C., then 5 ml. of ethanol is added. The mixture is stirred for 5 hours and then extracted with dichloromethane. The extracts are dried and concentrated and the residue is chromatographed on a silica gel "dry-column" to give N-allyl-2-(2-pyridyl)thioacetamide.
後処理
- customat 0°C
- stirringThe mixture is stirred for 5 hours
- extractionextracted with dichloromethane
- customThe extracts are dried
- concentrationconcentrated
- customthe residue is chromatographed on a silica gel "dry-column"
出典と根拠
- ORDレコード
- ord-fe12331de1834516a4ad0c1a2fe7fdbc
- 出典データセット
- uspto-grants-1976_04
- 特許番号
- US03950522
反応ノート
読み込み中…