Hydrochloric Acid → 5-(3-Methylbutoxy)-2-propylthiophenol

HRID 1606105ノート

反応式

HRID 1606105 の反応式
CN(C)C(=O)[S:4][C:5]1[CH:10]=[C:9]([O:11][CH2:12][CH2:13][CH:14]([CH3:16])[CH3:15])[CH:8]=[CH:7][C:6]=1[CH2:17][CH2:18][CH3:19].[OH-].[K+].CNC.Cl>O.C(O)COCCO>[CH3:15][CH:14]([CH3:16])[CH2:13][CH2:12][O:11][C:9]1[CH:8]=[CH:7][C:6]([CH2:17][CH2:18][CH3:19])=[C:5]([SH:4])[CH:10]=1

参加物

7

反応物 4

HCID 313Hydrochloric AcidHCID 674DimethylamineHCID 14797Potassium HydroxideHCID 21545974S-5-(3-methylbutoxy)-2-propylphenyl N,N-dimethylthiocarbamate

生成物 1

HCID 215459855-(3-Methylbutoxy)-2-propylthiophenol

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 8117Diethylene Glycol溶媒

実験手順

A solution of 136.1 parts of S-5-(3-methylbutoxy)-2-propylphenyl N,N-dimethylthiocarbamate and 280 parts of potassium hydroxide in 1000 parts of digol was stirred under nitrogen at 120° - 130° for 9 hours, after which no dimethylamine could be detected in the effluent nitrogen. The mixture was cooled, poured into 8000 parts of water and the resulting solution was acidified to pH 1 with hydrochloric acid. The mixture was extracted with ether and the latter was washed with water, dried over magnesium sulphate, filtered and evaporated to dryness to give 95.7 g of the desired product 5-(3-methylbutoxy)-2-propylthiophenol.

後処理

  1. temperatureThe mixture was cooled
  2. extractionThe mixture was extracted with ether
  3. washthe latter was washed with water
  4. dry with materialdried over magnesium sulphate
  5. filtrationfiltered
  6. customevaporated to dryness

出典と根拠

ORDレコード
ord-b1f54d07f00b402ab11bb08dbc9756b0
出典データセット
uspto-grants-1976_04
特許番号
US03952013

反応ノート

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