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Chloride → 2,5-Dimethyl-3,6-dihexyl-pyrazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Chloride | HCID 312 | — |
| 反応物 | Isocyanic acid | HCID 6347 | — |
| 反応物 | 2-Nonanone | HCID 13187 | — |
| 反応物 | 3-Oximino-2-nonanone | HCID 73682634 | — |
| 触媒 | Zinc | HCID 23994 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 2,5-Dimethyl-3,6-dihexyl-pyrazine | HCID 21814939 | — |
反応手順
5h. 2,5-Dimethyl-3,6-dihexyl-pyrazine was prepared by first forming 3-oximino-2-nonanone by reacting 2-nonanone with nitrocyl chloride according to the method of BOUVEAULT (loc.cit.). The autocondensation of two moles of the imino-ketone in the presence of zinc and acetic acid [according to the method described in Chimia 11, 310 (1957)] yielded 2,5-dimethyl-3,6-dihexyl-pyrazine which had a b.p. of 112°-120°C./0.01 mm. Hg.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03952024 |
| 出典データセット | uspto-grants-1976_04 |
| ORD ID | ord-34a45f4a20f24b4fb421621f1435b259 |
| 出典メモ | uspto-grants-1976_04 |