Furfural → Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2-(2-furanyl)ethenyl)-
反応式
[CH:1](=O)[C:2]1[O:6][CH:5]=[CH:4][CH:3]=1.[CH3:8][C:9]1[O:10][CH2:11][C:12]([CH3:15])([CH3:14])[N:13]=1>>[CH3:14][C:12]1([CH3:15])[N:13]=[C:9](/[CH:8]=[CH:1]/[C:2]2[O:6][CH:5]=[CH:4][CH:3]=2)[O:10][CH2:11]1参加物
3
実験手順
4,4-Dimethyl-2(2-α-furylethenyl)-2-oxazoline (P-1906) was prepared by reacting furfural with 2,4,4-trimethyl-2-oxazoline. The product had a boiling point of 87° at 0.14 mm and the nmr spectrum and infra-red absorption spectrum were consistent with the proposed structure. The oral LD0 by adminstration to mice was 50 mg/kg; the LD50 was 212 and the LD100 was 300 mg/kg.
出典と根拠
- ORDレコード
- ord-de937d0f163d4f4b9a7ff5ca53bb6eb6
- 出典データセット
- uspto-grants-1976_04
- 特許番号
- US03953432
反応ノート
読み込み中…