Methylamine → HCID 178484394、化合物

反応式

[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[N:7]=[CH:8][NH:9][CH:10]=1.[N+](C=C(SC)SC)([O-])=O.[N+:20]([CH:23]=[C:24](SC)[NH:25][CH2:26]CCCC1N=CNC=1)([O-:22])=[O:21].CN>>[N+:20]([CH:23]=[C:24]([NH:25][CH3:26])[NH:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[N:7]=[CH:8][NH:9][CH:10]=1)([O-:22])=[O:21]

参加物

反応物 4

HCID 6329Methylamine

HCID 836231,1-Bis(methylthio)-2-nitroethylene

HCID 1785038211-Nitro-2-methylthio-2-[4-(4-imidazolyl)butylamino]ethylene

HCID 178510959HCID 178510959、化合物

生成物 1

HCID 178484394HCID 178484394、化合物

実験手順

Reaction of 4-(4-aminobutyl)imidazole (from the dihydrobromide (3.6g) with 1-nitro-2,2-bis-methylthioethylene (2.0g) by the procedure of Example 4(i) and treatment of the resultant 1-nitro-2-methylthio-2-[4-(4-imidazolyl)butylamino]ethylene with methylamine according to the procedure of Example 3(ii) gives the title compound.