Dimethylacetamide → beta-Alanine, N-(3-acetamido-5-methylcarbamoyl-2,4,6-triiodobenzoyl)-
反応式
[CH3:1][NH:2][C:3]([C:5]1[C:6]([I:22])=[C:7]([C:16]([I:21])=[C:17]([NH2:20])[C:18]=1[I:19])[C:8]([NH:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14])=[O:9])=[O:4].[CH3:23][C:24](N(C)C)=[O:25]>>[CH3:1][NH:2][C:3]([C:5]1[C:6]([I:22])=[C:7]([C:16]([I:21])=[C:17]([NH:20][C:24](=[O:25])[CH3:23])[C:18]=1[I:19])[C:8]([NH:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14])=[O:9])=[O:4]参加物
3
実験手順
From 100.0 g. (0.155 mole) of N-(3-methylaminocarbonyl-5-amino-2,4,6-triiodobenzoyl)-β-alanine (IX c), m.p. about 190° C., in 190 ml. of dimethylacetamide, 70.1 g. (66.0%) of the above product, m.p. 295°-297°C. (under decomposition) is obtained with the addition of 28.7 ml. of acetyl chloride analogously to Example 14 and after reprecipitation from aqueous ammonia with hydrochloric acid.
出典と根拠
- ORDレコード
- ord-64ed42c530184792a31c9eefd758e447
- 出典データセット
- uspto-grants-1976_04