N-methyl-2-pyrrolidone → HCID 19851163、化合物
反応式
[NH2:1][C:2]1[CH:7]=[C:6](Cl)[CH:5]=[C:4]([NH2:9])[C:3]=1[N+:10]([O-:12])=[O:11].CN1CCC[C:15]1=[O:19]>C[O-].[Na+].CO>[NH2:1][C:2]1[CH:7]=[C:6]([O:19][CH3:15])[CH:5]=[C:4]([NH2:9])[C:3]=1[N+:10]([O-:12])=[O:11]参加物
5
実験手順
0.024 mole (4.5 g) of 2,6-diamino-4-chloronitrobenzene in 9 ml of N-methylpyrrolidone and 22.5 ml of 30% sodium methylate in methanol were refluxed for 4 hours 30 minutes. Upon dilution of the reaction medium with water, the desired product precipitated out. After filtering, water washing and vacuum drying in the presence of P2O5, the product obtained was recrystallized from toluene; a black insoluble product was eliminated by hot filtration. The desired product melted at 140° C.
後処理
- customUpon dilution of the reaction medium with water, the desired product precipitated out
- filtrationAfter filtering
- dry with materialwater washing and vacuum drying in the presence of P2O5
- customthe product obtained
- customwas recrystallized from toluene
- filtrationa black insoluble product was eliminated by hot filtration
出典と根拠
- ORDレコード
- ord-7f25a4c70d0e4104b5d01a9b0c606f95
- 出典データセット
- uspto-grants-1989_09
- 特許番号
- US04863482
反応ノート
読み込み中…