Sodium Methoxide → 2-(Betahydroxyethyl)amino-6-(beta-hydroxyethyl)amino-4-methoxynitrobenzene

HRID 1606852ノート

反応式

HRID 1606852 の反応式
[OH:1][CH2:2][CH2:3][NH:4][C:5]1[CH:10]=[C:9](Cl)[CH:8]=[C:7]([NH:12][CH2:13][CH2:14][OH:15])[C:6]=1[N+:16]([O-:18])=[O:17].[CH3:19][O-:20].[Na+]>CO>[OH:1][CH2:2][CH2:3][NH:4][C:5]1[CH:10]=[C:9]([O:20][CH3:19])[CH:8]=[C:7]([NH:12][CH2:13][CH2:14][OH:15])[C:6]=1[N+:16]([O-:18])=[O:17]

参加物

4

反応物 2

HCID 10942334Sodium MethoxideHCID 200710912-(beta-Hydroxyethyl)amino-6-(beta-hydroxyethyl)amino-4-chloronitrobenzene

生成物 1

HCID 198511562-(Betahydroxyethyl)amino-6-(beta-hydroxyethyl)amino-4-methoxynitrobenzene

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

0.09 mole (25 g) of 2-(β-hydroxyethyl)amino-6-(β-hydroxyethyl)amino-4-chloronitrobenzene in 100 ml of a 25% sodium methylate solution in methanol was heated over a boiling water bath. After heating for 1 hour 30 minutes the desired product was precipitated out of the reaction medium by adding 250 g of ice water. After filtering and hot drying under vacuum in the presence of P2O5, the desired product was recrystallized from 96° ethanol. It melted at 150° C.

出典と根拠

ORDレコード
ord-56011de210fd421f9aaef79035e30a3a
出典データセット
uspto-grants-1989_09
特許番号
US04863482

反応ノート

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