Acetic Acid → HCID 15085580、化合物

HRID 1607524ノート

反応式

HRID 1607524 の反応式
[CH3:1][NH:2][C:3](=[O:14])[NH:4][C:5]1[CH:9]=[CH:8][S:7][C:6]=1[C:10](OC)=[O:11].CN(C)C=O.C(O)(=O)C>[OH-].[K+]>[CH3:1][N:2]1[C:10](=[O:11])[C:6]2[S:7][CH:8]=[CH:9][C:5]=2[NH:4][C:3]1=[O:14]

参加物

5

反応物 3

HCID 176Acetic AcidHCID 6228DimethylformamideHCID 15085579HCID 15085579、化合物

生成物 1

HCID 15085580HCID 15085580、化合物

試薬・触媒・溶媒 1

HCID 14797Potassium Hydroxide溶媒

実験手順

Methyl 3-(N'-methylureido)thiophene-2-carboxylate (4,2 g, 20 mmol) was suspended with stirring in 5% aqueous potassium hydroxide (50 ml). Dimethylformamide was added until a clear solution was obtained. Stirring was continued for 30 min, whereafter the solution was neutralized with acetic acid. This afforded a crystalline precipitate of the title compound, which was separated by filtration and washed with water. M.p.>300° C.

後処理

  1. customwas obtained

出典と根拠

ORDレコード
ord-f9681ba618da4a4bbc084a425f84d94f
出典データセット
uspto-grants-1989_09
特許番号
US04866065

反応ノート

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