Formic Acid → 2'-(2,4-Difluorophenoxy)-4'-formylmethanesulfonanilide

関与物質

反応手順

A mixture of 4'-cyano-2'-(2,4-difluorophenoxy)methanesulfonanilide (1.5 g) and Raney's Nickel (1.5 g) in 75% formic acid (40 ml) was refluxed for 2 hours. The mixture was filtered and the filtrate was concentrated to dryness. The residue was recrystallized from ethanol to give pale yellow needles of 2'-(2,4-difluorophenoxy)-4'-formylmethanesulfonanilide (1.4 g).

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