Ethanol → 4-(4-Pentenoxy)-4'-nitrobiphenyl

HRID 1607781

反応式

HRID 1607781 の反応式
C(O)C.[OH:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:16]=[CH:15][C:14]([N+:17]([O-:19])=[O:18])=[CH:13][CH:12]=2)=[CH:7][CH:6]=1.[OH-].[K+].Br[CH2:23][CH2:24][CH2:25][CH:26]=[CH2:27]>O>[CH2:27]([O:4][C:5]1[CH:6]=[CH:7][C:8]([C:11]2[CH:16]=[CH:15][C:14]([N+:17]([O-:19])=[O:18])=[CH:13][CH:12]=2)=[CH:9][CH:10]=1)[CH2:26][CH2:25][CH:24]=[CH2:23]

参加物

6

反応物 4

HCID 702EthanolHCID 14797Potassium HydroxideHCID 707041-Pentene, 5-bromo-HCID 1380784-Hydroxy-4'-nitrobiphenyl

生成物 1

HCID 199012844-(4-Pentenoxy)-4'-nitrobiphenyl

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

To 400 ml ethanol is added 21.5 g of 4-hydroxy-4'-nitrobiphenyl, and the mixture is heated to reflux. A solution of 7.1 g KOH in 30 ml of water is added dropwise at reflux temperatures. After complete addition, 18 g of 5-bromo-1-pentene is added and the reaction medium is heated at reflux temperarure for about 15 hours. Ethanol is removed under vacuum from the cooled mixture, and the solid residue is slurried with water in a blender,filtered, washed with water, and air dried. The product then is recrystallized from 90/10 hexane/toluene, mp 74°-76° C.

後処理

  1. temperaturethe mixture is heated to reflux
  2. temperatureat reflux temperatures
  3. additionis added
  4. temperaturethe reaction medium is heated
  5. temperatureat reflux temperarure for about 15 hours
  6. customEthanol is removed under vacuum from the cooled mixture
  7. washwashed with water, and air
  8. customdried
  9. customThe product then is recrystallized from 90/10 hexane/toluene, mp 74°-76° C.

出典と根拠

ORDレコード
ord-933c51a8c2914f0085618e6639740dde
出典データセット
uspto-grants-1989_09
特許番号
US04867538

関連ノート

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