2-Quinolinecarboxaldehyde → HCID 54189210、化合物

HRID 1608176ノート

反応式

HRID 1608176 の反応式
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]=O.[C:13]1([CH3:23])[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([NH:21][NH2:22])=[O:20])[CH:14]=1>C(O)C>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]=[N:22][NH:21][C:19](=[O:20])[C:15]1[CH:16]=[CH:17][CH:18]=[C:13]([CH3:23])[CH:14]=1

参加物

4

反応物 2

HCID 796192-QuinolinecarboxaldehydeHCID 83082m-Toluohydrazide

生成物 1

HCID 54189210HCID 54189210、化合物収率 36.2%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of 3.3 gm (0.021 mole) of 2-quinolinecarboxaldehyde, 3.15 gm (0.021 mole) of m-toluic acid hydrazide and 150 ml of absolute ethanol is refluzed 10 hr. The hot solution is filtered then diluted with water until cloudy. The mixture is cooled to room temperature and then chilled. The solid is collected to give 2.2 gm (36%) of the title compound having a melting point of 187.5°-188° C. after recrystallizing from methylene chloride/diethyl ether.

後処理

  1. filtrationThe hot solution is filtered
  2. additionthen diluted with water until cloudy
  3. temperaturechilled
  4. customThe solid is collected

出典と根拠

ORDレコード
ord-7d855082c6a547da820846c7f6518b6e
出典データセット
uspto-grants-1989_09
特許番号
US04870082

反応ノート

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