Ethanol → HCID 19848597、化合物
反応式
C([O:4][CH2:5][CH2:6][CH:7]1[O:12][CH2:11][CH2:10][N:9]([C:13]([O:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:14])[CH2:8]1)(=O)C.[OH-].[K+].C(O)C>O>[OH:4][CH2:5][CH2:6][CH:7]1[O:12][CH2:11][CH2:10][N:9]([C:13]([O:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:14])[CH2:8]1参加物
5
実験手順
A mixture of 2-(2-acetoxyethyl)-4-benzyloxycarbonylmorpholine (24.5 g), potassium hydroxide (8.9 g), ethanol (40 ml), and water (40 ml) is refluxed for 30 minutes and concentrated under reduced pressure. Water is added to the residue and the mixture is extracted with diethyl ether. The organic layer is washed with water, dried over sodium sulfate, and evaporated to give the title compound (15 g) as an oil.
後処理
- temperatureis refluxed for 30 minutes
- concentrationconcentrated under reduced pressure
- additionWater is added to the residue
- extractionthe mixture is extracted with diethyl ether
- washThe organic layer is washed with water
- dry with materialdried over sodium sulfate
- customevaporated
出典と根拠
- ORDレコード
- ord-edb069b8cef14e5eb3fb84cb65bbe40a
- 出典データセット
- uspto-grants-1989_09
- 特許番号
- US04870074
反応ノート
読み込み中…