Boron → HCID 13527805、化合物

HRID 1608315ノート

反応式

HRID 1608315 の反応式
[CH3:1][Li].[C:3]([B:7](OC(C)C)[O:8][CH:9]([CH3:11])[CH3:10])([CH3:6])([CH3:5])[CH3:4].[B]>>[C:3]([B:7]([CH3:1])[O:8][CH:9]([CH3:11])[CH3:10])([CH3:6])([CH3:5])[CH3:4]

参加物

4

反応物 3

HCID 5462311BoronHCID 13183022Dipropan-2-yl tert-butylboronateHCID 178418348HCID 178418348、化合物

生成物 1

HCID 13527805HCID 13527805、化合物

実験手順

The reaction was run following the procedure described in Example 1 using methyllithium (38.4 mmol, 24.6 mL) and tert-butyldiisopropoxyborane (7.15 g, 38.3 mmol). Volatiles were removed at atmospheric pressure and the product distilled to yield 3.9 g (27.5 mmol, 73%), bp 90°-92° C. (741 mm Hg); proton NMR (CDCl3) δ 4.30 (septet, J=18 Hz, 1H), 1.15 (d, J=18 Hz, 6H), 0.83 (s, 9H), 0.30 (brs, 3H); boron NMR (neat) δ+52.9 ppm (s).

後処理

  1. customVolatiles were removed at atmospheric pressure
  2. distillationthe product distilled
  3. customto yield 3.9 g (27.5 mmol, 73%), bp 90°-92° C. (741 mm Hg)

出典と根拠

ORDレコード
ord-079faf83e1d24b46939e3ccac4bfd8aa
出典データセット
uspto-grants-1989_09
特許番号
US04870177

反応ノート

読み込み中…