Ammonia → HCID 178472081、化合物
反応式
C(O[CH:4]=[C:5]([C:11](=[O:22])[C:12]1[CH:17]=[C:16]([F:18])[C:15]([F:19])=[C:14]([F:20])[C:13]=1[F:21])[C:6]([O:8][CH2:9][CH3:10])=[O:7])C.[NH3:23]>CCO>[NH2:23][CH:4]=[C:5]([C:11](=[O:22])[C:12]1[CH:17]=[C:16]([F:18])[C:15]([F:19])=[C:14]([F:20])[C:13]=1[F:21])[C:6]([O:8][CH2:9][CH3:10])=[O:7]参加物
4
実験手順
12.8 g of ethyl 3-ethoxy-2-(2,3,4,5-tetrafluoro-benzoyl)-acrylate are initially introduced into 16 ml of EtOH. A mixture of 3.3 ml of concentrated aqueous NH3 solution and 10 ml of EtOH is added dropwise with ice cooling. The mixture is subsequently stirred for 2 hours. Ice-water is then added, and the precipitated solid is filtered off under suction. Yield: 8.7 g, melting point: 118°-119° C.
後処理
- additionis added dropwise with ice cooling
- filtrationthe precipitated solid is filtered off under suction
出典と根拠
- ORDレコード
- ord-eaf7f91e264b4a42a52d0cd301592bf8
- 出典データセット
- uspto-grants-1989_09
- 特許番号
- US04870182
反応ノート
読み込み中…