alpha-Hydroxyacetophenone → HCID 776385、化合物

反応式

[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](Cl)=[O:5].O[CH2:12][C:13]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[O:14]>>[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]1[O:5][C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=2[C:13](=[O:14])[CH:12]=1

参加物

反応物 2

HCID 68490alpha-Hydroxyacetophenone

HCID 702762-Methylbenzoyl chloride

生成物 1

HCID 776385HCID 776385、化合物

実験手順

7 is prepared from 2-methylbenzoyl chloride (8) and 2-hydroxyacetophenone by the procedure of Example 1. The material is purified by vacuum column (eluting with 10% ethyl acetate in hexane), yielding 7 with a melting point of 45.5°-47.5° C.

後処理

customThe material is purified by vacuum column (eluting with 10% ethyl acetate in hexane)
customyielding 7 with a melting point of 45.5°-47.5° C.

出典と根拠

ORDレコード: ord-9d226149205e428da9ef06116dc8a5e7
出典データセット: uspto-grants-1995_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05399584

反応ノート

読み込み中…