Hydrochloric Acid → HCID 178478916、化合物
反応式
[ClH:1].[CH3:2][N:3]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([CH2:12][C:13]#[N:14])=[CH:4]1.C1([OH:21])C=CC=CC=1>C(OCC)C>[ClH:1].[CH3:2][N:3]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([CH2:12][C:13](=[NH:14])[OH:21])=[CH:4]1参加物
5
実験手順
Hydrogen chloride was bubbled through a solution of 3 g (176 mmol) of 1-methylindole-3-acetonitrile and 8.28 g (88 mmol) of phenol in 70 ml of dry diethyl ether for 2 hours and the resulting solution was left to stand for 4 days. The solvent was removed under reduced pressure. The residual gum was triturated with diethyl ether to give 1.4 g (30%) of 1-methyl3-indoleacetimidate hydrochloride in the form of a purple solid of melting point 119° C.
後処理
- waitthe resulting solution was left
- customThe solvent was removed under reduced pressure
- customThe residual gum was triturated with diethyl ether
出典と根拠
- ORDレコード
- ord-11eba358ae8947c09a5c870e388488b5
- 出典データセット
- uspto-grants-1995_03
- 特許番号
- US05399712
反応ノート
読み込み中…