3-(Chloromethyl)pyridine hydrochloride → 7-Bromo-2-pyridin-3-ylmethyl-2H-phthalazin-1-one

反応式

[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[N:7][NH:8][C:9]2=[O:12])=[CH:4][CH:3]=1.Cl.Cl[CH2:15][C:16]1[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=1>>[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[N:7][N:8]([CH2:15][C:16]3[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=3)[C:9]2=[O:12])=[CH:4][CH:3]=1

参加物

反応物 2

HCID 233943-(Chloromethyl)pyridine hydrochloride

HCID 222653177-bromo-2H-phthalazin-1-one

生成物 1

HCID 544303767-Bromo-2-pyridin-3-ylmethyl-2H-phthalazin-1-one

実験手順

The titled compound was prepared from 7-bromo-1 (2H)-phthalazinone and 3-chloromethylpyridine hydrochloride in the same manner as in Example 10 (1) a).

出典と根拠

ORDレコード: ord-1d6077715b0f46e3b664ef594bcac4f8
出典データセット: uspto-grants-1995_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05401756

反応ノート

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