Ethanol → Ethyl 2-hydroxy-2-phenylpropanoate
反応式
[C:1]1([C:7]([CH3:12])([OH:11])[C:8]([OH:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(=O)(=O)(O)O.[CH2:18](O)[CH3:19]>CCOCC>[C:1]1([C:7]([CH3:12])([OH:11])[C:8]([O:10][CH2:18][CH3:19])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1参加物
5
実験手順
(±)-Phenyllactic acid (4.96 g) and 1/2 ml concentrated sulfuric acid in 150 ml absolute ethanol is refluxed for 18 hours. Solvent is stripped, the residue is dissolved in ether, and extracted with saturated sodium bicarbonate solution. The ether is dried, filtered, and stripped to leave (±)-ethyl phenyllactate. NMR (CDCl3): δ1.3 (t, 3H), 3.0 (d of d, 1H), 3.1 (d of d, 1H), 4.2 (q, 2H), 4.4 (d of d, 1H), 7.3 (m, 5H).
後処理
- extractionextracted with saturated sodium bicarbonate solution
- dry with materialThe ether is dried
- filtrationfiltered
出典と根拠
- ORDレコード
- ord-a2e094f4293f41d5bfddf16caeeec860
- 出典データセット
- uspto-grants-1995_03
- 特許番号
- US05401772
反応ノート
読み込み中…