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Triethylamine → ethyl-2-(2,4-dimethoxyphenyl)-4,5-dihydro-thiazole-4-(R)-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Ethyl L-cysteinate | HCID 13359 | — |
| 反応物 | 2,4-Dimethoxybenzonitrile | HCID 77750 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | ethyl-2-(2,4-dimethoxyphenyl)-4,5-dihydro-thiazole-4-(R)-carboxylate | HCID 17747724 | — |
反応手順
2,4-Dimethoxybenzonitrile, (R)-cysteine ethyl ester and about 5 equivalents of triethylamine are refluxed in ethanol for about 6–8 hours to obtain ethyl-2-(2,4-dimethoxyphenyl)-4,5-dihydro-thiazole-4-(R)-carboxylate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06982335B2 |
| 出典データセット | uspto-grants-2006_01 |
| ORD ID | ord-495c069965fd4491b5366627893a9e8e |
| 出典メモ | uspto-grants-2006_01 |