N-Methylisopropylamine → 4-bromo-2-fluoro-N-methyl-N-(1-methylethyl)-benzamide

反応式

[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[C:4]([F:11])[CH:3]=1.[CH3:12][NH:13][CH:14]([CH3:16])[CH3:15]>>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([N:13]([CH3:12])[CH:14]([CH3:16])[CH3:15])=[O:8])=[C:4]([F:11])[CH:3]=1

参加物

反応物 2

HCID 78485N-Methylisopropylamine

HCID 3026814-Bromo-2-fluorobenzoic acid

生成物 1

HCID 247056274-bromo-2-fluoro-N-methyl-N-(1-methylethyl)-benzamide

実験手順

The sub-title compound was prepared by the method of example 18 step a) using 4-bromo-2-fluorobenzoic acid and N-methyl-2-propanamine.

出典と根拠

ORDレコード: ord-74c6c848bd1c4c16975e719d9c933089
出典データセット: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07737135B2

反応ノート

読み込み中…