2-(1-Chloroethyl)-5-fluoropyridine → 2-[[2-Amino-5-[1-(5-fluoro-2-pyridinyl)ethylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol

反応式

[Cl:20][CH:21]([CH3:22])[c:23]1[n:24][cH:25][c:26]([F:29])[cH:27][cH:28]1.[NH2:1][c:2]1[s:3][c:4]2[c:5]([n:6][c:7]([SH:18])[n:8][c:9]2[NH:10][CH:11]([CH2:12][OH:13])[CH2:14][CH:15]([CH3:16])[CH3:17])[n:19]1>>[NH2:1][c:2]1[s:3][c:4]2[c:5]([n:6][c:7]([S:18][CH:21]([CH3:22])[c:23]3[n:24][cH:25][c:26]([F:29])[cH:27][cH:28]3)[n:8][c:9]2[NH:10][CH:11]([CH2:12][OH:13])[CH2:14][CH:15]([CH3:16])[CH3:17])[n:19]1

参加物

反応物 2

HCID 591868842-(1-Chloroethyl)-5-fluoropyridine

HCID 178445193HCID 178445193、化合物

生成物 1

HCID 875004612-[[2-Amino-5-[1-(5-fluoro-2-pyridinyl)ethylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol

出典と根拠

ORDレコード: ord-b7ea1e2ae4fa46de80a7d2b7034fe761
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…