2-(1-(4-[4-(benzyloxy)phenyl]butyl}-1H-imidazol-2-yl)-1-ethanol → 4-[4-[2-(2-hydroxyethyl)-1H-imidazol-1-yl]butyl]phenol
反応式
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][CH2:17][CH2:18][N:19]2[CH:23]=[CH:22][N:21]=[C:20]2[CH2:24][CH2:25][OH:26])=[CH:11][CH:10]=1)C1C=CC=CC=1>[C].[Pd]>[OH:26][CH2:25][CH2:24][C:20]1[N:19]([CH2:18][CH2:17][CH2:16][CH2:15][C:12]2[CH:11]=[CH:10][C:9]([OH:8])=[CH:14][CH:13]=2)[CH:23]=[CH:22][N:21]=1参加物
3
実験手順
Using 2-(1-{4-[4-(benzyloxy)phenyl]butyl}-1H-imidazol-2-yl)-1-ethanol (10.67 g) and 10% palladium carbon (1.6 g), the same reaction as Reference Example 11-(v) was carried out to yield the titled compound (5.3 g).
後処理
- customthe same reaction as Reference Example 11-(v)
出典と根拠
- ORDレコード
- ord-0442f9a2410a443e806f82946b74729d
- 出典データセット
- uspto-grants-2006_01
- 特許番号
- US06984653B2
反応ノート
読み込み中…